GeneTex
United States (US)

HLA-DR + HLA-DP antibody [HL-40]

Cat No. GTX28085

Host Mouse
Clonality Monoclonal
Clone Name HL-40
Isotype IgG2a
Application WB, FACS, IP
Reactivity Human, Pig
APPLICATION

Application Note

FACS: Use at an assay dependent concentration. IP: Use at an assay dependent concentration. WB: Use at an assay dependent concentration. Optimal dilutions/concentrations should be determined by the end user.

Specificity/Sensitivity

Common epitope on b-chain of human HLA-DR and HLA-DP.Also reacts with porcine MHC class II antigens (SLA-D gene products).
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline pH 7.4 containing 15mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Immunogen

Burkitt lymphoma cell line Raji.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Background

The antibody is useful for detection of HLA-DR and HLA-DP positive B-cells, T-cells and monocytes in cell suspensions, in frozen sections as well as in formalin fixed paraffin embedded tissue sections. The antibody is also useful for characterization of leukemias and lymphomas. In experimental settings it can be used for selective removal of antigen carrying cells by complement mediated cytotoxicity. The antibody has excellent staining properties in histology.
Package List Price ($)
$ 319