PRODUCT
Summary
The LN3 antibody reacts with a member of the human MHC Class II antigens, HLA-DR. The HLA-DR antigen is expressed on human antigen presenting cells including B lymphocytes, monocytes, macrophages, dendritic cells, and activated T lymphocytes. HLA-DR is a dimeric protein composed of alpha and beta subunits and is involved in the presentation of peptide antigens to CD4+ T cells.
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
0.125 μg (5 μl) for 10⁵-10⁸ cells in 100 μl sample per test |
Not tested in other applications.
PROPERTIES
Form
Liquid
Buffer
10mM NaH₂PO₄, 150mM NaCl, 0.1% Gelatin
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Concentration
0.025 mg/ml (Please refer to the vial label for the specific concentration.)
Purification
Purified by affinity chromatography
From tissue culture supernatant
Conjugation
Phycoerythrin-Cyanine7 (PE-Cy7)
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
major histocompatibility complex, class II, DR alpha , major histocompatibility complex, class II, DR beta 1 , major histocompatibility complex, class II, DR beta 3 , major histocompatibility complex, class II, DR beta 4 , major histocompatibility complex, class II, DR beta 5 , HLA-DRA1 , DRB1 , HLA-DR1B , HLA-DRB , SS1 , DRB3 , HLA-DPB1 , HLA-DR1B , HLA-DR3B , DR4 , DRB4 , HLA-DR4B
Cellular Localization
Cell membrane , Endoplasmic reticulum membrane , Endosome membrane , Lysosome membrane , Cell membrane; Single-pass type I membrane protein
Database
Research Area
DATA IMAGES
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GTX01489-10 FACS Image
FACS analysis of human peripheral blood monocytes using GTX01489-10 HLA-DR antibody [LN3] (PE-Cy7). Solid lone : primary antibody Dashed line : isotype control antibody amount : 0.125 μg (5 μl)
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REFERENCE
REVIEW
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