GeneTex

  • Country / Location Selection

United States (US)

HLA-G antibody [MEM-G/2]

Anti-HLA-G antibody [MEM-G/2] used in Western Blot (WB). GTX78394
Anti-HLA-G antibody [MEM-G/2] used in IHC (Paraffin sections) (IHC-P). GTX78394

Cat. No. GTX78394

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MEM-G/2

Isotype

 IgG1

Application

 WB, IHC-P, IHC-Fr

Reactivity

 Human
Package
100 μg ($399)
See all HLA-G products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-P Assay dependent
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

38 kDa. ( Note )

Product Note

This antibody recognizes the free heavy chain of all the HLA-G isoforms.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Immunogen

Bacterially expressed recombinant HLA-G heavy chain (denatured).

Purification

Purified by precipitation and chromatography

Conjugation

Unconjugated

RRID

AB_625686

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

HLAG , MHCG , major histocompatibility complex, class I, G , HLA-G

Cellular Localization

Cell membrane,Secreted

Background

HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-HLA-G antibody [MEM-G/2] used in Western Blot (WB). GTX78394

GTX78394 WB Image

WB analysis of HLA-G1 transfectants (LCL-HLA-G1) using GTX78394 HLA-G antibody [MEM-G/2].

Anti-HLA-G antibody [MEM-G/2] used in IHC (Paraffin sections) (IHC-P). GTX78394

GTX78394 IHC-P Image

IHC-P analysis of kidney allograft biopsy tissue using GTX78394 HLA-G antibody [MEM-G/2].

REFERENCE

Application Reference

Vietsch EE et al. Front Immunol 2023; 14 : 1230306 B cell immune profiles in dysbiotic vermiform appendixes of pancreatic cancer patients.
Submit a Reference

REVIEW

There are currently no reviews for HLA-G antibody [MEM-G/2] (GTX78394). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399