GeneTex
United States (US)

HMGA2 antibody, Internal

GTX88326_2415_WB_18121411_926.jpg

Cat No. GTX88326

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1-3μg/ml
Not tested in other applications.

Calculated MW

12 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88326-PEP).

Specificity/Sensitivity

This antibody is expected to recognize both reported isoforms (NP_003474.1; NP_003475.1) and is not expected to cross-react with HMGA1.

Predict Reactivity

Dog(>80% identity)
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Concentration

0.50mg/ml

Antigen Species

Human

Immunogen

Peptide with sequence C-KAAQKKAEATGEK, from the internal region of the protein sequence according to NP_003474.1; NP_003475.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

STQTL9 Antibody , HMGIC Antibody , HMGI C Antibody , LIPO Antibody , BABL Antibody

Background

This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
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Database

Research Area

DATA IMAGES
GTX88326_2415_WB_18121411_926.jpg

GTX88326 WB Image

WB analysis of human heart lysate using GTX88326 HMGA2 antibody, Internal.
Dilution : 1µg/ml
Loading : 35µg protein in RIPA buffer