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HNF1 beta antibody [HNF1B/9518]

Anti-HNF1 beta antibody [HNF1B/9518] used in IHC (Paraffin sections) (IHC-P). GTX05009

Cat. No. GTX05009

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 HNF1B/9518

Isotype

 IgG2a

Application

 IHC-P

Reactivity

 Human
Package
100 μg ($529)
See all HNF1 beta products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1-2μg/ml

Note :

IHC-P
Antigen retrieval : heat mediated tissue sections in 10mM Tris with 1mM EDTA (pH 9.0) followed by cooling at RT for 20 minutes.
Not tested in other applications.

Positive Control

Human kidney, pancreas or liver tissue

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA (Please contact us for PBS only format)

Preservative

0.05% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment (1-200 aa) of human HNF1B protein

Purification

Purified by Protein A/G

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

FJHN,HNF1 homeobox B,HNF1B,HNF1beta,HNF2,HPC11,LFB3,MODY5,TCF2,VHNF1,HNF1 BETA

Cellular Localization

Nucleus

Background

This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]

Database

Research Area

DATA IMAGES

Anti-HNF1 beta antibody [HNF1B/9518] used in IHC (Paraffin sections) (IHC-P). GTX05009

GTX05009 IHC-P Image

IHC-P analysis of human liver carcinoma tissue using GTX05009 HNF1 beta antibody [HNF1B/9518].
Lower left corner : Negative control

REFERENCE

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REVIEW

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Package List Price ($)
$ 529