GeneTex
United States (US)

HNMT antibody

GTX53566_742_IHC-P_18122100_687.jpg
GTX53566_574_ICC-IF_18121410_368.jpg
GTX53566_1562_WB_18121410_961.jpg

Cat No. GTX53566

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1000
ICC/IF 1:10-1:50
IHC-P 1:10-1:50
Not tested in other applications.

Calculated MW

33 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS, 0.09% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human HNMT.

Purification

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

HNMT-S2 Antibody , HNMT-S1 Antibody , HMT Antibody , histamine N-methyltransferase Antibody

Background

In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX53566_742_IHC-P_18122100_687.jpg

GTX53566 IHC-P Image

IHC-P analysis of human hepatocarcinoma using GTX53566 HNMT antibody.

GTX53566_574_ICC-IF_18121410_368.jpg

GTX53566 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX53566 HNMT antibody.
Green : HNMT
Blue : DAPI

GTX53566_1562_WB_18121410_961.jpg

GTX53566 WB Image

WB analysis of HeLa cell lysate (35ug/lane) using GTX53566 HNMT antibody.

Package List Price ($)
$ 329