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HNMT antibody

Anti-HNMT antibody used in IHC (Paraffin sections) (IHC-P). GTX65997
Anti-HNMT antibody used in Western Blot (WB). GTX65997
Anti-HNMT antibody used in Immunoprecipitation (IP). GTX65997

Cat. No. GTX65997

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, IP

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all HNMT products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
IP 1:20 - 1:50
Not tested in other applications.

Calculated MW

33 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 1-292 of human HNMT (NP_008826.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

histamine N-methyltransferase , HMT , HNMT-S1 , HNMT-S2 , MRT51

Cellular Localization

Cytoplasm

Background

In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-HNMT antibody used in IHC (Paraffin sections) (IHC-P). GTX65997

GTX65997 IHC-P Image

IHC-P analysis of mouse heart tissue using GTX65997 HNMT antibody.
Dilution : 1:100

Anti-HNMT antibody used in Western Blot (WB). GTX65997

GTX65997 WB Image

WB analysis of various sample lysates using GTX65997 HNMT antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-HNMT antibody used in Immunoprecipitation (IP). GTX65997

GTX65997 IP Image

IP analysis of HT-29 cell lysate using GTX65997 HNMT antibody.
Antibody amount : 1μg / 200μg lysate
Dilution : 1:1000

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399