GeneTex
United States (US)

HNRPDL antibody

HNRPDL-antibody-GTX87722-IHC-1_18121411_293.jpg

Cat No. GTX87722

Host Rabbit
Clonality Polyclonal
Application IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

We recommend the following starting dilutions:

IHC: 1:50~1:100
ELISA: 1:1000

Optimal dilutions should be determined experimentally by the end user.

Calculated MW

46 kDa. ( Note )

Specificity/Sensitivity

HNRPDL Antibody detects endogenous levels of total HNRPDL protein.
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human HNRPDL.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Heterogeneous Nuclear Ribonucleoprotein D Like,Hnrnp,Hnrpdl,Jktbp,Jktbp2,Lgmd1G,Laauf1,Hnrnpdl

Cellular Localization

Shuttles between the nucleus and the cytoplasm in a TNPO1-dependent manner.

Background

Acts as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes (By similarity). Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter (By similarity). Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or poly(C) RNA homopolymers. Binds to the 5'-ACUAGC-3' RNA consensus sequence.

Database

DATA IMAGES
HNRPDL-antibody-GTX87722-IHC-1_18121411_293.jpg

GTX87722 IHC-P Image

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using HNRPDL Antibody. The picture on the right is treated with the synthesized peptide.

Package List Price ($)
$ 339