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HP1 alpha antibody [3G2-H10-A6]

Anti-HP1 alpha antibody [3G2-H10-A6] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX49194
Anti-HP1 alpha antibody [3G2-H10-A6] used in Western Blot (WB). GTX49194

Cat No. GTX49194

Host

Mouse

Clonality

Monoclonal

Clone Name

3G2-H10-A6

Isotype

IgG2b

Application

WB, ICC/IF

Reactivity

Human, Mouse
Package
100 μg ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ICC/IF Assay dependent
Not tested in other applications.

Calculated MW

26 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Purified mouse monoclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified recombinant human CBX5 protein fragments expressed in E.coli.

Purification

Affinity purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Chromobox 5 , Hel25 , Hp1 , Hp1A , Cbx5

Cellular Localization

Nucleus. Chromosome

Background

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Database

Research Area

DATA IMAGES

Anti-HP1 alpha antibody [3G2-H10-A6] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX49194

GTX49194 ICC/IF Image

ICC/IF analysis of HeLa cells using HP1 alpha antibody at a dilution of 1:300.

Anti-HP1 alpha antibody [3G2-H10-A6] used in Western Blot (WB). GTX49194

GTX49194 WB Image

WB analysis of indicated lysates using HP1 alpha antibody at a dilution of 1:1,000.

REFERENCE

There are currently no references for HP1 alpha antibody [3G2-H10-A6] (GTX49194). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for HP1 alpha antibody [3G2-H10-A6] (GTX49194). Be the first to share your experience with this product.
SDS
Glycerol.pdf
Sodium Azide.pdf