GeneTex

  • Country / Location Selection

United States (US)

HP1 alpha antibody

Anti-HP1 alpha antibody used in Western Blot (WB). GTX00897

Cat. No. GTX00897

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human
Package
50 μg ($399)
See all HP1 alpha products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000-1:3000
ICC/IF 1:200-1:1000
Not tested in other applications.

Calculated MW

22 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Filter-sterilized 0.12M Sodium Phosphate buffer (pH7.4), 50% Glycerol

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.37 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The product is prepared by immunizing rabbit with the synthetic peptide CEDAENKEKETAKS corresponding to the amino acid sequence 179-191 of human HP1 alpha

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

chromobox 5 , CBX5 , HEL25 , HP1 , HP1A , HP1 alpha

Cellular Localization

Nucleus,Chromosome,Centromere

Background

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-HP1 alpha antibody used in Western Blot (WB). GTX00897

GTX00897 WB Image

WB analysis of MCF-7 whole cell lysate using GTX00897 HP1 alpha antibody.
Dilution : 1:1000

REFERENCE

There are currently no references for HP1 alpha antibody (GTX00897). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for HP1 alpha antibody (GTX00897). Be the first to share your experience with this product.
Submit a Review
SDS
Glycerol.pdf
Package List Price ($)
$ 399