GeneTex
United States (US)

HP1 gamma antibody [5G10-F7-A12]

GTX16488_IP_18121410_803.jpg
GTX16488_IHC-P_18121410_363.jpg
GTX16488_ICCIF_18121410_423.jpg
GTX16488_WB_18121410_979.jpg

Cat No. GTX16488

Host Mouse
Clonality Monoclonal
Clone Name 5G10-F7-A12
Isotype IgG1
Application WB, ICC/IF, IHC-P, IP, ID
Reactivity Human, Mouse, Rat, Hamster, Monkey
APPLICATION

Calculated MW

21 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.75 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified recombinant human HP1-gamma protein fragments expressed in E.coli.

Purification

Affinity purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Chromobox 3,Hech,Hp1-Gamma,Hp1Hs-Gamma,Cbx3

Background

At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011]

Database

DATA IMAGES
GTX16488_IP_18121410_803.jpg

GTX16488 IP Image

IP analysis was performed with HeLa lysates and either control IgG PR HP1 gamma antibody [5G10-F7-A12]. The precipitates were detected by the same antibody.

GTX16488_IHC-P_18121410_363.jpg

GTX16488 IHC-P Image

IHC-P analysis of prostate cancer using HP1 gamma antibody [5G10-F7-A12] at a dilution of 1:200. Antigen retrieval was performed by pressure cooking in citrate buffer (pH 6.0).

GTX16488_ICCIF_18121410_423.jpg

GTX16488 ICC/IF Image

ICC/IF analysis of HeLa cells using HP1 gamma antibody [5G10-F7-A12] at a dilution of 1:200.

GTX16488_WB_18121410_979.jpg

GTX16488 WB Image

WB analysis of various cell lysates using HP1 gamma antibody [5G10-F7-A12] at a dilution of 1:1000.

Package List Price ($)
$ 319