APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:2000-1:10000 |
| Assay dependent |
| Assay dependent |
Not tested in other applications.
Calculated MW
Product Note
chicken, Xenopus, Drosophila, and zebrafish
Predict Reactivity
Zebrafish, Drosophila, Chicken, Xenopus(>80% identity)
PROPERTIES
Form
Liquid
Buffer
Filter-sterilized 0.12M Sodium Phosphate buffer (pH7.4), 50% Glycerol
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.75 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
The product is prepared by immunizing rabbit with the synthetic peptide WHSCPEDEAQ-C corresponding to the C-terminal sequence of human HP1 gamma and purified by affinity purification with the peptide.
Purification
Purified IgG
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
chromobox 3 , CBX3 , HECH , HP1GAMMA , HP1Hsgamma , HP1 gamma
Cellular Localization
Nucleus
Background
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011]
Database
Research Area
DATA IMAGES
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GTX00898 ICC/IF Image
ICC/IF analysis of BHK cells using GTX00898 HP1 gamma antibody.
Fixation : 4% PFA
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GTX00898 WB Image
WB analysis of BHK cell Lysate using GTX00898 HP1 gamma antibody.
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REFERENCE
There are currently no references for HP1 gamma antibody (GTX00898). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for HP1 gamma antibody (GTX00898). Be the first to share your experience with this product.
