*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
chicken, Xenopus, Drosophila, and zebrafish
Zebrafish, Drosophila, Chicken, Xenopus(>80% identity)
Filter-sterilized 0.12 M sodium phosphate buffer (pH 7.4), 50% glycerol
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.75 mg/ml (Please refer to the vial label for the specific concentration.)
The product is prepared by immunizing rabbit with the synthetic peptide WHSCPEDEAQ-C corresponding to the C-terminal sequence of human HP1 gamma and purified by affinity purification with the peptide.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
chromobox 3 , CBX3 , HECH , HP1GAMMA , HP1Hsgamma , HP1 gamma
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011]
GTX00898 WB Image
WB analysis of BHK cell Lysate using GTX00898 HP1 gamma antibody.
GTX00898 ICC/IF Image
ICC/IF analysis of BHK cells using GTX00898 HP1 gamma antibody.
Fixation : 4% PFA