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HP1 gamma antibody

KO/KD
Anti-HP1 gamma antibody used in Western Blot (WB). GTX55664
Anti-HP1 gamma antibody used in IHC (Paraffin sections) (IHC-P). GTX55664
Anti-HP1 gamma antibody used in IHC (Paraffin sections) (IHC-P). GTX55664
Anti-HP1 gamma antibody used in Western Blot (WB). GTX55664
Anti-HP1 gamma antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55664
Anti-HP1 gamma antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55664
Anti-HP1 gamma antibody used in IHC (Paraffin sections) (IHC-P). GTX55664

Cat. No. GTX55664

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all HP1 gamma products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

21 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-183 of human CBX3 (NP_009207.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

chromobox 3 , HECH , HP1-GAMMA , HP1Hs-gamma

Cellular Localization

Nucleus

Background

At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011]

Database

Research Area

DATA IMAGES

Anti-HP1 gamma antibody used in Western Blot (WB). GTX55664

GTX55664 WB Image

KO/KD

WB analysis of normal (control) and knockout (KO) HeLa cell lysate using GTX55664 HP1 gamma antibody.
Dilution : 1:500
Loading : 25μg per lane

Anti-HP1 gamma antibody used in IHC (Paraffin sections) (IHC-P). GTX55664

GTX55664 IHC-P Image

IHC-P analysis of human esophageal cancer tissue using GTX55664 HP1 gamma antibody.
Dilution : 1:50

Anti-HP1 gamma antibody used in IHC (Paraffin sections) (IHC-P). GTX55664

GTX55664 IHC-P Image

IHC-P analysis of mouse liver tissue using GTX55664 HP1 gamma antibody.
Dilution : 1:50

Anti-HP1 gamma antibody used in Western Blot (WB). GTX55664

GTX55664 WB Image

WB analysis of various sample lysates using GTX55664 HP1 gamma antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-HP1 gamma antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55664

GTX55664 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX55664 HP1 gamma antibody.
Blue : DAPI
Dilution : 1:100

Anti-HP1 gamma antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55664

GTX55664 ICC/IF Image

ICC/IF analysis of C6 cells using GTX55664 HP1 gamma antibody.
Blue : DAPI
Dilution : 1:100

Anti-HP1 gamma antibody used in IHC (Paraffin sections) (IHC-P). GTX55664

GTX55664 IHC-P Image

IHC-P analysis of rat brain tissue using GTX55664 HP1 gamma antibody.
Dilution : 1:50

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399