*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji
Mouse, Rat, Bovine, Pig(>80% identity)
0.1M Tris-Glycine (pH7), 10% Glycerol
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.92 mg/ml (Please refer to the vial label for the specific concentration.)
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human HPS3. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 , BLOC2S1 , SUTAL
This gene encodes a protein containing a potential clathrin-binding motif, consensus dileucine signals, and tyrosine-based sorting signals for targeting to vesicles of lysosomal lineage. The encoded protein may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 3. Alternate splice variants exist, but their full length sequence has not been determined. [provided by RefSeq]
GTX107745 IHC-P Image
Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using HPS3(GTX107745) antibody at 1:500 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min
GTX107745 ICC/IF Image
HPS3 antibody [C3], C-term detects HPS3 protein at cytoplasm by immunofluorescent analysis.
Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: HPS3 protein stained by HPS3 antibody [C3], C-term (GTX107745) diluted at 1:500.
Blue: Hoechst 33343 staining.
GTX107745 WB Image
Sample(30 μg of whole cell lysate)
D:HeLa S3 (GTX14654)
E:Hep G2 (GTX27900)
7.5% SDS PAGE
GTX107745 diluted at 1:1000