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HYPB/SETD2 antibody, Internal

Anti-HYPB/SETD2 antibody, Internal used in Western Blot (WB). GTX88922

Cat No. GTX88922

Host

Goat

Clonality

Polyclonal

Isotype

IgG

Application

WB

Reactivity

Mouse
Package
100 μg ($379)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.5-2μg/ml
Not tested in other applications.

Calculated MW

288 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88922-PEP).

Predict Reactivity

Human, Dog, Pig(>80% identity)

PROPERTIES

Form

Liquid

Buffer

TBS pH7.3, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-ERDPDKQTQNKE, from the internal region of the protein sequence according to NP_054878.5.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

SET domain containing 2, histone lysine methyltransferase , HBP231 , HIF-1 , HIP-1 , HSPC069 , HYPB , KMT3A , LLS , SET2 , p231HBP

Cellular Localization

Nucleus

Background

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]

Database

Research Area

DATA IMAGES

Anti-HYPB/SETD2 antibody, Internal used in Western Blot (WB). GTX88922

GTX88922 WB Image

WB analysis of mouse fibroblast lysates (transiently expressing different siRNA in second and third lane) using GTX88922 HYPB/SETD2 antibody, Internal.
Dilution : 0.5μg/ml
Loading : 35μg protein in RIPA buffer

REFERENCE

There are currently no references for HYPB/SETD2 antibody, Internal (GTX88922). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for HYPB/SETD2 antibody, Internal (GTX88922). Be the first to share your experience with this product.
SDS
Sodium Azide.pdf
Package List Price ($)
$ 379