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Heme Oxygenase 1 antibody

KO/KD Orthogonal
Anti-Heme Oxygenase 1 antibody used in Western Blot (WB). GTX101147
Anti-Heme Oxygenase 1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX101147
Anti-Heme Oxygenase 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX101147
Anti-Heme Oxygenase 1 antibody used in Western Blot (WB). GTX101147
Anti-Heme Oxygenase 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX101147
Anti-Heme Oxygenase 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX101147
Anti-Heme Oxygenase 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX101147
Anti-Heme Oxygenase 1 antibody used in ELISA (ELISA). GTX101147
Anti-Heme Oxygenase 1 antibody used in Western Blot (WB). GTX101147
Anti-Heme Oxygenase 1 antibody used in Western Blot (WB). GTX101147
Anti-Heme Oxygenase 1 antibody used in Western Blot (WB). GTX101147

Cat. No. GTX101147

Reference 61
7

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, ELISA, Sandwich ELISA

Reactivity

 Human, Mouse, Rat, Monkey
Package
100 μl ($399),
25 μl ($169)
See all Heme Oxygenase 1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
ICC/IF 1:100-1:1000
IHC-P 1:100-1:1000
ELISA Assay dependent
Sandwich ELISA Assay dependent

Note :

Sandwich ELISA
Capture : GTX633677, Detection: GTX101147
Not tested in other applications.

Calculated MW

33 kDa. ( Note )

Positive Control

Raw264.7 , C2C12

Predict Reactivity

Bovine, Dog, Pig(>80% identity)

PROPERTIES

Form

Liquid

Buffer

1XPBS pH7, 20% Glycerol

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.45 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human Heme Oxygenase 1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_1950502

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

heme oxygenase 1 , HMOX1D , HO-1 , HSP32 , bK286B10

Cellular Localization

Microsome , Endoplasmic reticulum

Background

Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-Heme Oxygenase 1 antibody used in Western Blot (WB). GTX101147

GTX101147 WB Image

KO/KD

Wild-type (WT) and Heme Oxygenase 1 knockout (KO) HeLa cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with Heme Oxygenase 1 antibody (GTX101147) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.

Anti-Heme Oxygenase 1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX101147

GTX101147 ICC/IF Image

Orthogonal

Heme Oxygenase 1 antibody detects Heme Oxygenase 1 protein at endoplasmic reticulum and nucleus by immunofluorescent analysis.
Sample: Mock and treated HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: Heme Oxygenase 1 stained by Heme Oxygenase 1 antibody (GTX101147) diluted at 1:500.
Blue: Fluoroshield with DAPI (GTX30920).

Anti-Heme Oxygenase 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX101147

GTX101147 IHC-P Image

Heme Oxygenase 1 antibody detects Heme Oxygenase 1 protein at cytoplasm on human renal carcinoma by immunohistochemical analysis.
Sample: Paraffin-embedded human renal carcinoma .
Heme Oxygenase 1 antibody (GTX101147) diluted at 1:500.

Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Anti-Heme Oxygenase 1 antibody used in Western Blot (WB). GTX101147

GTX101147 WB Image

Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with Heme Oxygenase 1 antibody (GTX101147) diluted at 1:1500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-Heme Oxygenase 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX101147

GTX101147 IHC-P Image

Heme Oxygenase 1 antibody detects Heme Oxygenase 1 protein at cytoplasm by immunohistochemical analysis.
Sample: Paraffin-embedded mouse liver.
Heme Oxygenase 1 stained by Heme Oxygenase 1 antibody (GTX101147) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-Heme Oxygenase 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX101147

GTX101147 IHC-P Image

Heme Oxygenase 1 antibody detects Heme Oxygenase 1 protein at cytoplasm by immunohistochemical analysis.
Sample: Paraffin-embedded rat spleen.
Heme Oxygenase 1 stained by Heme Oxygenase 1 antibody (GTX101147) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-Heme Oxygenase 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX101147

GTX101147 IHC-P Image

Heme Oxygenase 1 antibody detects Heme Oxygenase 1 protein at cytoplasm by immunohistochemical analysis.
Sample: Paraffin-embedded mouse spleen.
Heme Oxygenase 1 stained by Heme Oxygenase 1 antibody (GTX101147) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-Heme Oxygenase 1 antibody used in ELISA (ELISA). GTX101147

GTX101147 ELISA Image

Sandwich ELISA detection of recombinant full-length Heme Oxygenase 1 protein using GTX633677 as capture antibody at concentration of 5 μg/mL and GTX101147 as detection antibody at concentration of 1 μg/mL. Rabbit IgG antibody (HRP) (GTX213110-01) was diluted at 1:10000 and used to detect the primary antibody.

Anti-Heme Oxygenase 1 antibody used in Western Blot (WB). GTX101147

GTX101147 WB Image

Orthogonal

Untreated (–) and treated (+) HeLa whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with Heme Oxygenase 1 antibody (GTX101147) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-Heme Oxygenase 1 antibody used in Western Blot (WB). GTX101147

GTX101147 WB Image

Rat tissue extract (50 μg) was separated by 12% SDS-PAGE, and the membrane was blotted with Heme Oxygenase 1 antibody (GTX101147) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-Heme Oxygenase 1 antibody used in Western Blot (WB). GTX101147

GTX101147 WB Image

Whole cell extract (30 μg) was separated by 12% SDS-PAGE, and the membrane was blotted with Heme Oxygenase 1 antibody (GTX101147) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

REFERENCE

Application Reference

Shou JW et al. Int J Mol Sci 2023; 24 (14) Berberine Reduces Lipid Accumulation in Obesity via Mediating Transcriptional Function of PPARδ.
Consoli V et al. Int J Mol Sci 2023; 24 (13) Evaluation of the Antioxidant and Antiangiogenic Activity of a Pomegranate Extract in BPH-1 Prostate Epithelial Cells.
Salvatore Giunta et al. Pharmaceuticals 2023; 16 (7) : 974 Drug-Repurposing Strategy for Dimethyl Fumarate
Application : WB
Kogami M et al. Oncol Lett 2023; 26 (1) : 313 Fenofibrate attenuates the cytotoxic effect of cisplatin on lung cancer cells by enhancing the antioxidant defense system in?vitro.
Mariko Kogami et al. Oncol. Lett. 2023; 26 : 313 Fenofibrate attenuates the cytotoxic effect of cisplatin on lung cancer cells by enhancing the antioxidant defense system in vitro
Application : WB
Reactivity : Human
Show More +
Submit a Reference

REVIEW

Heme Oxygenase 1 antibody Cat. No. GTX101147

Rating
( Average 5 based on 7 users reviews)
Application
Western Blot(WB)
( Average 5 based on 6 users reviews)
IHC (Paraffin sections)(IHC-P)
( Average 5 based on 1 users reviews)
Anti-Heme Oxygenase 1 antibody used in Western Blot (WB). GTX101147
Date : Anonymous submitted on 24-Jul-2023
Score :
Application Tested : WB
Sample Species : Rat
Figure Note : The data was peer reviewed and published in the 2022 in Front Cell Neurosci. PMID: 35496911
Anti-Heme Oxygenase 1 antibody used in Western Blot (WB). GTX101147
Date : Anonymous submitted on 24-Jul-2023
Score :
Application Tested : WB
Sample Species : Rat
Figure Note : The data was peer reviewed and published in the 2022 in Front Cell Neurosci. PMID: 35496911
Anti-Heme Oxygenase 1 antibody used in Western Blot (WB). GTX101147
Date : Anonymous submitted on 24-Jul-2023
Score :
Application Tested : WB
Sample Species : Rat
Figure Note : The data was peer reviewed and published in the 2022 in Front Cell Neurosci. PMID: 35496911
Anti-Heme Oxygenase 1 antibody used in Western Blot (WB). GTX101147
Date : Anonymous submitted on 10-Aug-2021
Score :
Application Tested : WB
Sample Species : Ms
Figure Note : The data was peer reviewed and published in the journal Cell Death Dis in 2017.PMID: 28055010
Anti-Heme Oxygenase 1 antibody used in Western Blot (WB). GTX101147
Date : Anonymous submitted on 18-Mar-2021
Score :
Application Tested : WB
Sample Species : Hu
Figure Note : The data was peer reviewed and published in the journal Int J Mol Sci in 2019. PMID: 30621167
Anti-Heme Oxygenase 1 antibody used in Western Blot (WB). GTX101147
Date : Anonymous submitted on 18-Mar-2021
Score :
Application Tested : WB
Sample Species : Hu
Figure Note : The data was peer reviewed and published in the journal Cells in 2019. PMID: 31366086
Anti-Heme Oxygenase 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX101147
Date : Anonymous submitted on 21-Oct-2020
Score :
Application Tested : IHC-P
Sample Species : Hu
Sample : Normal spleen tissue
Fixation : EDTA buffer, 0.3°C
Primary Antibody : 1:500, 4°C, 16Hr
Show More +
Submit a Review
Application Reference
Shou JW et al. Int J Mol Sci 2023; 24 (14) Berberine Reduces Lipid Accumulation in Obesity via Mediating Transcriptional Function of PPARδ.
Consoli V et al. Int J Mol Sci 2023; 24 (13) Evaluation of the Antioxidant and Antiangiogenic Activity of a Pomegranate Extract in BPH-1 Prostate Epithelial Cells.
Salvatore Giunta et al. Pharmaceuticals 2023; 16 (7):974 Drug-Repurposing Strategy for Dimethyl Fumarate
Application : WB
Kogami M et al. Oncol Lett 2023; 26 (1):313 Fenofibrate attenuates the cytotoxic effect of cisplatin on lung cancer cells by enhancing the antioxidant defense system in?vitro.
Mariko Kogami et al. Oncol. Lett. 2023; 26:313 Fenofibrate attenuates the cytotoxic effect of cisplatin on lung cancer cells by enhancing the antioxidant defense system in vitro
Application : WB
Reactivity : Human
YP Lee et al. Am J Cancer Res 2023; Combination treatment of cordycepin and radiation induces MA-10 mouse Leydig tumor cell death via ROS accumulation and DNA damage
Application : WB
Reactivity : Mouse
Zhang W et al. Oxid Med Cell Longev 2023; 2023:9966355 Tubeimoside I Ameliorates Doxorubicin-Induced Cardiotoxicity by Upregulating SIRT3.
Application : WB
Reactivity : Mouse, Rat
Lai W et al. Nanomaterials (Basel) 2022; 12 (22) Bacterial Magnetosomes Release Iron Ions and Induce Regulation of Iron Homeostasis in Endothelial Cells.
Application : WB
Reactivity : Human
Pritchard KA Jr et al. PLoS One 2022; 17 (8):e0269564 Role of endoplasmic reticulum stress in impaired neonatal lung growth and bronchopulmonary dysplasia.
Valeria Consoli et al. Int J Mol Sci 2022; 23 (10) Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells.
Application : WB
Reactivity : Human
Valeria Ciaffaglione et al. Molecules 2022; 27 (10) Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia.
Application : WB
Reactivity : Human
Yang Yang et al. Front Cell Neurosci 2022; 16:783346 Heme Oxygenase-1 Protects Hair Cells From Gentamicin-Induced Death.
Application : WB, ICC/IF
Reactivity : Mouse, Rat
Angela Filoni et al. Life (Basel) 2022; 12 (2) Immune Disregulation in Cutaneous Squamous Cell Carcinoma of Patients with Recessive Dystrophic Epidermolysis Bullosa: A Single Pilot Study.
Application : IHC-P
Reactivity : Human
Xing Ren et al. Neuropsychiatr Dis Treat 2022; 18:513-524 Senegenin Inhibits Aβ1-42-Induced PC12 Cells Apoptosis and Oxidative Stress via Activation of the PI3K/Akt Signaling Pathway.
Application : WB
Reactivity : Rat
Ryan Houston et al. Mol Biol Cell 2021; 32 (21):ar32 Discovery of bactericides as an acute mitochondrial membrane damage inducer.
Application : WB
Reactivity : Human
Ting-Yu Chao et al. Food Sci Nutr 2021; 9 (9):4758-4769 Bracteanolide A abrogates oxidative stress-induced cellular damage and protects against hepatic ischemia and reperfusion injury in rats.
Application : WB
Reactivity : Human
Li J et al. Ecotoxicol Environ Saf 2021; 228:112918 Effective-component compatibility of Bufei Yishen formula protects COPD rats against PM2.5-induced oxidative stress via miR-155/FOXO3a pathway.
Application : WB
Reactivity : Rat
Shih HJ et al. Sci Rep 2021; 11 (1):22925 Differential expression of hypoxia-inducible factors related to the invasiveness of epithelial ovarian cancer.
Application : WB, IHC-P
Reactivity : Human
Cazzato G et al. Biomolecules 2021; 11 (8) HMGB1-TIM3-HO1: A New Pathway of Inflammation in Skin of SARS-CoV-2 Patients? A Retrospective Pilot Study.
Application : IHC-P
Reactivity : Human
Fallica AN et al. J Med Chem 2021; 64 (18):13373-13393 Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent In Vitro Antiproliferative Activity.
Application : WB
Reactivity : Human
Song L et al. Brain Res Bull 2021; 177:81-91 Antidepressant effect of catalpol on corticosterone-induced depressive-like behavior involves the inhibition of HPA axis hyperactivity, central inflammation and oxidative damage probably via dual regulation of NF-κB and Nrf2.
Application : WB
Reactivity : Mouse
Mineo S et al. Arch Oral Biol 2021; 129:105215 Rice bran-derived protein fractions enhance sulforaphane-induced anti-oxidative activity in gingival epithelial cells.
Sorrenti V et al. Biomolecules 2021; 11 (6) Tin Mesoporphyrin Selectively Reduces Non-Small-Cell Lung Cancer Cell Line A549 Proliferation by Interfering with Heme Oxygenase and Glutathione Systems.
Application : WB
Reactivity : Human
Raineri A et al. Molecules. 2021; 26 (16):5027 3,5-Dicaffeoylquinic Acid Lowers 3T3-L1 Mitotic Clonal Expansion and Adipocyte Differentiation by Enhancing Heme Oxygenase-1 Expression.
Application : WB
Reactivity : Mouse
Hori Y et al. Cells 2021; 10 (5) Aromatic-Turmerone Analogs Protect Dopaminergic Neurons in Midbrain Slice Cultures through Their Neuroprotective Activities.
Application : WB
Reactivity : Mouse
Zeng J et al. Phytother Res 2021; 35 (6):3418-3427 Theaflavin alleviates oxidative injury and atherosclerosis progress via activating microRNA-24-mediated Nrf2/HO-1 signal.
Application : WB
Hossain KFB et al. Ecotoxicol Environ Saf 2021; 207:111320 Zinc-pretreatment triggers glutathione and Nrf2-mediated protection against inorganic mercury-induced cytotoxicity and intrinsic apoptosis in PC12?cells.
Application : WB
Reactivity : Rat
Kostka T et al. Arch Toxicol 2020; 94 (11):3911-3927 Synthesis and in vitro characterization of the genotoxic, mutagenic and cell-transforming potential of nitrosylated heme.
Application : WB
Hossain KFB et al. Food Chem Toxicol 2020; 146:111819 Amelioration of butylated hydroxytoluene against inorganic mercury induced cytotoxicity and mitochondrial apoptosis in PC12?cells via antioxidant effects.
Application : WB
Chen HY et al. Chem Biol Interact 2020; 331:109249 TGF-β1 signaling protects retinal ganglion cells from oxidative stress via modulation of the HO-1/Nrf2 pathway.
Application : WB
Reactivity : Mouse
Seiwert N et al. Cell Death Dis 2020; 11 (9):787 Heme oxygenase 1 protects human colonocytes against ROS formation, oxidative DNA damage and cytotoxicity induced by heme iron, but not inorganic iron.
Application : WB
Reactivity : Human
Batubara I et al. Antioxidants (Basel) 2020; 9 (8) The Antiaging Effect of Active Fractions and Ent-11α-Hydroxy-15-Oxo-Kaur-16-En-19-Oic Acid Isolated from Adenostemma lavenia (L.) O. Kuntze at the Cellular Level.
Application : WB
Reactivity : Mouse
Mohd Salman et al. Dis Model Mech. 2020; 13 (8):dmm045021 Nrf2/HO-1 mediates the neuroprotective effects of pramipexole by attenuating oxidative damage and mitochondrial perturbation after traumatic brain injury in rats.
Application : WB
Reactivity : Rat
Mohd Salman et al. Mol Neurobiol. 2020; 57 (6):2870-2885 Tannic Acid Provides Neuroprotective Effects Against Traumatic Brain Injury Through the PGC-1α/Nrf2/HO-1 Pathway.
Application : WB
Reactivity : Rat
Kuang Y et al. Mol Med Rep 2020; 22 (4):2783-2790 Protective effect of dimethyl fumarate on oxidative damage and signaling in cardiomyocytes.
Application : WB
Reactivity : Rat
Hseu YC et al. Oxid Med Cell Longev 2020; 2020:2576823 The Antiaging Activity of Ergothioneine in UVA-Irradiated Human Dermal Fibroblasts via the Inhibition of the AP-1 Pathway and the Activation of Nrf2-Mediated Antioxidant Genes.
Application : WB
Reactivity : Human
Binte Hossain KF et al. Ecotoxicol Environ Saf 2020; 192:110238 Regulatory effects of dihydrolipoic acid against inorganic mercury-mediated cytotoxicity and intrinsic apoptosis in PC12?cells.
Application : WB
Reactivity : Rat
Tsai YS et al. Cancer Sci 2019; 110 (4):1208-1219 Prothymosin-α enhances phosphatase and tensin homolog expression and binds with tripartite motif-containing protein 21 to regulate Kelch-like ECH-associated protein 1/nuclear factor erythroid 2-related factor 2 signaling in human bladder cancer.
Hseu YC et al. Oxid Med Cell Longev 2019; 2019:4098674 Zerumbone Exhibits Antiphotoaging and Dermatoprotective Properties in Ultraviolet A-Irradiated Human Skin Fibroblast Cells via the Activation of Nrf2/ARE Defensive Pathway.
Application : WB
Reactivity : Human
Huang SY et al. Biomolecules 2019; 9 (8) The Protective Effect of Hispidin against Hydrogen Peroxide-Induced Oxidative Stress in ARPE-19 Cells via Nrf2 Signaling Pathway.
Application : WB
Reactivity : Human
Neitzel C et al. Cells 2019; 8 (8) Lipoic Acid Synergizes with Antineoplastic Drugs in Colorectal Cancer by Targeting p53 for Proteasomal Degradation.
Application : WB
Reactivity : Human
Hseu YC et al. Biochem Pharmacol 2019; 164:299-310 The in vitro and in vivo depigmenting activity of Coenzyme Q10 through the down-regulation of α-MSH signaling pathways and induction of Nrf2/ARE-mediated antioxidant genes in UVA-irradiated skin keratinocytes.
Application : WB
Reactivity : Human
Ko PH et al. Chin Med 2019; 14:10 Identifying the functions and biomarkers of Codonopsis pilosula and Astragalus membranaceus aqueous extracts in hepatic cells.
Application : WB
Reactivity : Human
Chu Y et al. Int J Mol Sci 2019; 20 (1) Protective Effects and Mechanisms of N-Phenethyl Caffeamide from UVA-Induced Skin Damage in Human Epidermal Keratinocytes through Nrf2/HO-1 Regulation.
Application : WB
Reactivity : Human
Yeh CN et al. Cancer Manag Res 2018; 10:6049-6059 HO-1 is a favorable prognostic factor for HBV-HCC patients who underwent hepatectomy.
Cai J et al. Cell Rep 2018; 25 (7):1708-1717.e5 autophagy ablation in adipocytes induces * resistance and reveals roles for lipid peroxide and nrf2 signaling in adipose-liver crosstalk.
Application : WB
Reactivity : Mouse
Yeom M et al. Front Pharmacol 2018; 9:1314 High Doses of Bupleurum falcatum Partially Prevents Estrogen Deficiency-Induced Bone Loss With Anti-osteoclastogenic Activity Due to Enhanced iNOS/NO Signaling.
Application : WB
Reactivity : Rat
Huang KF et al. J Cell Physiol 2018; (Epub) A new copper ionophore DPMQ protects cells against ultraviolet B irradiation by inhibiting the TRPV1 channel.
Application : WB
Reactivity : Human
Cheng YM et al. Oncotarget 2018; 9 (41):26342-26352 PSMD4 is a novel therapeutic target in chemoresistant colorectal cancer activated by cytoplasmic localization of Nrf2.
Application : WB
Reactivity : Human
Tsai MS et al. Toxicol Lett 2018; 290:97-109 Kaempferol protects against propacetamol-induced acute liver injury through CYP2E1 inactivation, UGT1A1 activation, and attenuation of oxidative stress, inflammation and apoptosis in mice.
Application : WB
Reactivity : Mouse
Hseu YC et al. J Dermatol Sci 2018; (Epub) Trans-cinnamic acid attenuates UVA-induced photoaging through inhibition of AP-1 activation and induction of Nrf2-mediated antioxidant genes in human skin fibroblasts.
Application : WB
Reactivity : Human
Lin JT et al. Food Funct. 2017; 8 (3):1245-1253 Molecular mechanisms of the effects of the ethanolic extract of Muntingia calabura Linn. fruit on lipopolysaccharide-induced pro-inflammatory mediators in macrophages.
Application : WB
Huang YC et al. Toxicol Appl Pharmacol 2017; 329:128-139 galangin ameliorates *-induced nephrotoxicity by attenuating oxidative stress, inflammation and cell death in mice through inhibition of erk and nf-kappab signaling.
Application : WB
Reactivity : Mouse
Ugun-Klusek A et al. Cell Death Dis 2017; 8 (1):e2531 Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway.
Application : WB
Reactivity : Mouse
Xu YM et al. Oncotarget 2016; 7 (5):6146-58 Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells.
Reactivity : Human
Asada D et al. Pediatr Int 2016; (Epub) The tolerance to ischemia reperfusion injury in a congenital heart disease model.
Application : WB
Reactivity : Rat
Lin PL et al. Free Radic Biol Med 2016; 95:121-132 Cytoplasmic localization of Nrf2 promotes colorectal cancer with more aggressive tumors via upregulation of PSMD4.
Application : WB, IHC-P
Reactivity : Monkey
Yu JS et al. PLoS One 2016; 11 (3):e0152236 Sulforaphane Suppresses Hepatitis C Virus Replication by Up-Regulating Heme Oxygenase-1 Expression through PI3K/Nrf2 Pathway.
Application : WB
Reactivity : Human
Hseu YC et al. journal of functional foods 2015; 12:303-318 The dermato-protective effects of lucidone from Lindera erythrocarpa through the induction of Nrf2-mediated antioxidant genes in UVA-irradiated human skin keratinocytes.
Application : WB
Reactivity : Human
Hseu YC et al. Free Radic Biol Med 2015; 86:102-17 Dermato-protective properties of ergothioneine through induction of Nrf2/ARE-mediated antioxidant genes in UVA-irradiated Human keratinocytes.
Application : WB
Reactivity : Human
Yeh CH et al. J Cell Physiol 2015; Baicalein decreases hydrogen peroxide-induced damage to NG108-15 cells via upregulation of Nrf2.
Application : WB
Reactivity : Mouse
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