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Hepatitis C virus Core Antigen antibody [A1/3D1]

Cat. No. GTX18700

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 A1/3D1

Isotype

 IgG1

Application

 ELISA

Reactivity

 Hepatitis C virus
Package
250 μg ($399)
See all Hepatitis C virus Core Antigen products

APPLICATION

Application Note

ELISA: Use at an assay dependent dilution. GTX18700 was tested using indirect ELISA method. The testing plates were coated with HCV non-structural protein (NS), capsid protein (C) and the mixture of NS and C separately. The neat culture supernatant of hybridoma showed a strong reaction with HCV capsid protein (OD492 value > 2.0) and mixture of NS and C (OD492 value >1.5), and have no reaction with HCV non-structural protein (OD492 value < 0.03). Is unsuitable for WB. Optimal dilutions/concentrations should be determined by the end user.

Product Note

GTX18700 detects recombinant capsid protein C (CPC), envelope protein M (EPM) core; amino acids 1-142) and synthetic capsid protein C (amino acids 1-61). GTX18700 recognizes different antigenic determinants of Hepatitis C Core Antigen.

PROPERTIES

Form

Liquid

Buffer

0.01M PBS pH7.2

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Hepatitis C virus

Immunogen

Synthetic peptides derived from HCV capsid protein.

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Hepatitis C Virus Core , HCV Core

Background

Hepatitis C virus (HCV) is the primary cause of non-A, non-B hepatitis and results in most HCV infected people developing chronic infections, liver cirrhosis and hepatocellular carcinoma. The 21 kDa core protein of HCV is well conserved among different HCV genotypes and may suppress hepatitis B virus replication in a phosphorylation dependent manner.

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399
Custom Conjugations