Preservative: 0.1% Sodium Azide. Constituents: 0.01M PBS. pH 7.2
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
4 mg/ml (Please refer to the vial label for the specific concentration.)
Hepatitis C virus
Recombinant fragment (polypeptide containing core NS3 and NS4 regions).
>95% pure. Sodium sulfate precipitation and ion-exchange chromatography.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Hepatitis C Virus Core+NS3+NS4 , HCV Core+NS3+NS4
Core and non-structural regions.
HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non-structural protein necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha.