Preservative: 0.1% Sodium Azide. Constituents: 0.01M PBS. pH 7.2
Hepatitis C virus
Recombinant fragment (polypeptide containing core NS3 and NS4 regions).
>95% pure. Sodium sulfate precipitation and ion-exchange chromatography.
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Core and non-structural regions.
HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non-structural protein necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha.