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Hepatitis C virus NS3 protein antibody [113]

Cat No. GTX18664

Host

Mouse

Clonality

Monoclonal

Clone Name

113

Isotype

IgG1

Application

WB, ELISA

Reactivity

Hepatitis C virus
Package
250 μg ($379)

APPLICATION

Application Note

ELISA: Use at an assay dependent dilution. WB: Use at a concentration of 0.1 - 1 μg/ml. Predicted molecular weight: 60 kDa. Optimal dilutions/concentrations should be determined by the end user. GTX18664 will allow visualization of 100 ng/lane of both recombinant chimeric HCV polyprotein and recombinant NS-3 Protein. No reaction is seen with synthetic NS-3.

Product Note

GTX18664 reacts with recombinant NS-3 (1252aa-1477aa), synthetic NS-3 (1378aa-1458aa), and recombinant chimeric HCV polyprotein (60 kDa). No cross reaction can be seen with recombinant CPC* + EPM** (core) (amino acids 1-142), synthetic CPC* (amino acids 1-61), and synthetic NS-4 protein (amino acids 1689-1735).

PROPERTIES

Form

Liquid

Buffer

0.01M PBS pH7.2

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Hepatitis C virus

Immunogen

Purified recombinant chimeric HCV polyprotein (555 amino acids)

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Hepatitis C Virus Serine protease NS3 , Hepatitis C Virus NS3 , HCV Serine protease NS3 , HCV NS3

Cellular Localization

Cell Membrane, Cytoplasmic and Plasma membrane

Background

HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non-structural proteins necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha.

Research Area

REFERENCE

There are currently no references for Hepatitis C virus NS3 protein antibody [113] (GTX18664). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Hepatitis C virus NS3 protein antibody [113] (GTX18664). Be the first to share your experience with this product.
SDS
PBS.pdf
Package List Price ($)
$ 379
Custom Conjugations