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Hepatitis C virus NS3 protein antibody [20-8]

Cat. No. GTX18663

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 20-8

Isotype

 IgG1

Application

 WB, ELISA, IHC

Reactivity

 Hepatitis C virus
Package
250 μg ($399)
See all Hepatitis C virus NS3 protein products

APPLICATION

Application Note

ELISA: Use at an assay dependent dilution. WB: Use at a concentration of 1 μg/ml. Predicted molecular weight: 60 kDa. GTX18663 will allow visualization of 0.1 ug/lane of synthetic NS-3 protein. Optimal dilutions/concentrations should be determined by the end user.

Product Note

Specific for synthetic NS-3 Protein (amino acids 1378-1458). No cross reaction with HCV capsid region and other non-structural regions.

PROPERTIES

Form

Liquid

Buffer

0.01M PBS pH7.0

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Hepatitis C virus

Immunogen

A highly antigenic polypeptide consisting of essential sequences of at least 60 residues in length, which were selected from genes encoding the NS-3 region of Chinese HCV strains.

Purification

Protein G purified

Conjugation

Unconjugated

RRID

AB_423333

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Hepatitis C Virus Serine protease NS3 , Hepatitis C Virus NS3 , HCV Serine protease NS3 , HCV NS3

Cellular Localization

Cell Membrane, Cytoplasmic and Plasma membrane

Background

HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non-structural proteins necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha.

Research Area

REFERENCE

Application Reference

Letendre S et al. J Infect Dis 2007; 196 (3) : 361-70 Pathogenesis of hepatitis C virus coinfection in the brains of patients infected with HIV.
Application : IHC
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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399
Custom Conjugations