This antibody can be used on formalin-fixed, paraffin-embedded tissue sections. Prolonged fixation in buffered formalin can destroy the epitope. In a standard three-step streptavidin-biotin method a dilution of 1:40 may be used as a guideline. When using paraffin-embedded and formalin-fixed tissues, high temperature antigenic unmasking technique is strongly recommended for consistent and reproducible results. This product can also be used on frozen tissue sections. The optimal conditions should be determined by the individual laboratory.
This antibody is specific against c-erbB-3 oncoprotein that is expressed in a variety of human normal, fetal and neoplastic epithelial tissues.
10mM PBS, pH 7.4, with 0.2% BSA and <0.1% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.1mg/ml(Please refer to the vial label for the specific concentration.)
Synthetic peptide corresponding to a site on the cytoplasmic domain of the human c-erbB-3 oncoprotein.
From hybridoma culture supernatant
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
c-erbB-3, c-erbB3, p45-sErbB3, p85-sErbB3, ErbB-3, MDABF1, ErbB3, P21860, erbB3-S, p180ErbB3, p85sErbB3, erbB3S, cerbB3, p45sErbB3, 190151, MGC88033, 2065, HER3, MDA-BF-1, p180-ErbB3, ErbB 3, c erbB3, erbB3 S, c erbB 3, MDA BF 1, p45 sErbB3, p85 sErbB3, p
Type I membrane protein and Secreted
This antibody reacts with normal gastrointestinal epithelium as well as gastrointestinal and breast tumors, resulting in a cytoplasmic staining pattern.