GeneTex
United States (US)

Histone H3 antibody

Histone-H3-antibody_IHC-P_GTX27834-1_18121411_147.jpg

Cat No. GTX27834

Host Sheep
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, IP
Reactivity Human, Bovine
APPLICATION

Application Note

For IP: Use at an assay dependent dilution. For WB: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the researcher
PROPERTIES

Form

Liquid

Buffer

Phosphate-buffered saline

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

2.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Intact calf Histone H3 complex to ribosomal RNA

Purification

Protein G affinity purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Cellular Localization

Nuclear

Background

In diploid eukaryotic cells, the chromatin fibers are about 20nM in diameter. They consist of two major components in equal amounts, DNA and basic proteins called histones. Histones are believed to be regularly arranged in the deep grove of the DNA helix. The recurring positive charges of the histones form electrostatic associations with the negatively charged phosphate groups of DNA making the DNA more stable and flexible. This allows for the supercoiling of the chromatin fibers.

Research Area

DATA IMAGES
Histone-H3-antibody_IHC-P_GTX27834-1_18121411_147.jpg

GTX27834 IHC-P Image

Histone H3 human prostate formalin fixed, paraffin embedded 5 ug/ml

Package List Price ($)
$ 319