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Hrk antibody

Orthogonal
Anti-Hrk antibody used in Western Blot (WB). GTX54049
Anti-Hrk antibody used in Western Blot (WB). GTX54049

Cat. No. GTX54049

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse, Rat
Package
100 μg ($519)
See all Hrk products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 2-5μg/ml

Note :

WB
This antibody detects a band of approximately 13kDa in mouse pancreas tissue lysate.
Not tested in other applications.

Calculated MW

10 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

15 amino acid peptide from near the centre of human HRK (NP_003797).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887838

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

harakiri, BCL2 interacting protein , DP5 , HARAKIRI

Cellular Localization

Mitochondrion

Background

This gene encodes a member of the BCL-2 protein family. Members of this family are involved in activating or inhibiting apoptosis. The encoded protein localizes to intracellular membranes. This protein promotes apoptosis by interacting with the apoptotic inhibitors BCL-2 and BCL-X(L) via its BH3 domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]

Database

Research Area

DATA IMAGES

Anti-Hrk antibody used in Western Blot (WB). GTX54049

GTX54049 WB Image

WB analysis of mouse pancreas tissue lysate using GTX54049 Hrk antibody at (A) 2.5 and (B) 5ug/ml.

Anti-Hrk antibody used in Western Blot (WB). GTX54049

GTX54049 WB Image

Orthogonal

The data was published in the journal Oncotarget in 2018. PMID: 29416632

REFERENCE

Application Reference

Dong Z et al. Oncotarget 2018; 9 (1) : 512-523 HDAC inhibitor PAC-320 induces G2/M cell cycle arrest and apoptosis in human prostate cancer.
Application : WB
Reactivity : Human
Submit a Reference

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 519