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Human APRIL protein, DDDDK tag (active, multimeric)

Cat. No. GTX65680-pro

Application

 Functional Assay

Species

 Human
Package
10 μg ($419)
See all APRIL protein products
PRODUCT

Summary

Multimeric Proteins are high activity constructs in which two trimeric TNFSF ligands are linked via the oligomeric collagen domain of ACRP30 [ACRP30headless] and therefore mimic the membrane-bound forms of the proteins.

APPLICATION

Application Note

Stimulates B cell proliferation.

Product Note

Binds to human and mouse BCMA and TACI. Binds to proteoglycans.

PROPERTIES

Form

Lyophilized powder

Buffer

Reconstitute with 100μl ddH₂O to 0.1mg/ml. Lyophilized from 0.2μm-filtered PBS.

Preservative

No preservative

Storage

Store at -20ºC or below. After reconstitution, keep as concentrated solution. Aliquot and avoid freeze-thaw cycles.

Region/Sequence

N-terminal DDDDK-Tag; the extracellular domain of human APRIL (a.a. 88-233) is fused at the N-terminus to human ACRP30headless (a.a. 16-108).

Expression System

HEK293 cells

Purity

??95% by SDS-PAGE.

Endotoxin

< 0.01 EU/μg

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

TNF superfamily member 13 , APRIL , CD256 , TALL-2 , TALL2 , TNLG7B , TRDL-1 , UNQ383/PRO715 , ZTNF2

Database

  • Gene ID: 8741 TNFSF13

Research Area

REFERENCE

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SDS
PBS.pdf
Package List Price ($)
$ 419