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Human Apolipoprotein CIII protein, His and GST tag

Human Apolipoprotein CIII protein, His and GST tag. GTX03431-pro

Cat. No. GTX03431-pro

Species

 Human
Package
50 μg ($429)
See all Apolipoprotein CIII products

APPLICATION

Calculated MW

11 kDa. ( Note )

Observed MW

34 kDa.

PROPERTIES

Form

Lyophilized powder

Buffer

Reconstitute with ddH₂O to 0.1-1.0 mg/mL. Do not vortex. Lyophilized from 100mM NaHCO₃ pH8.3, 500mMNaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose.

Preservative

ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Region/Sequence

N-terminal His and GST Tagged; Ser21~Ala99

Expression System

E. coli

Purity

>90%

Endotoxin

< 1 EU/弮g (Determined by LAL assay)

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

apolipoprotein C3 , APOCIII

Cellular Localization

Secreted

Background

This gene encodes a protein component of triglyceride (TG)-rich lipoproteins (TRLs) including very low density lipoproteins (VLDL), high density lipoproteins (HDL) and chylomicrons. The encoded protein plays a role in role in the metabolism of these TRLs through multiple modes. This protein has been shown to promote the secretion of VLDL1, inhibit lipoprotein lipase enzyme activity, and delay catabolism of TRL remnants. Mutations in this gene are associated with low plasma triglyceride levels and reduced risk of ischemic cardiovascular disease, and hyperalphalipoproteinemia, which is characterized by elevated levels of high density lipoprotein (HDL) and HDL cholesterol in human patients. This gene and other related genes comprise an apolipoprotein gene cluster on chromosome 11. [provided by RefSeq, Sep 2017]

Database

Research Area

DATA IMAGES

Human Apolipoprotein CIII protein, His and GST tag. GTX03431-pro

GTX03431-pro Image

SDS-PAGE of GTX03431-pro Human Apolipoprotein CIII protein, His and GST tag.

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Package List Price ($)
$ 429