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Human Autotaxin (mature) protein, His tag (active)

Human Autotaxin (mature) protein, His tag (active). GTX02798-pro
Human Autotaxin (mature) protein, His tag (active). GTX02798-pro

Cat. No. GTX02798-pro

Application

 Functional Assay

Species

 Human
Package
50 μg ($729)
See all Autotaxin protein products

APPLICATION

Application Note

The reaction rate of GTX02798-pro Human Autotaxin (mature) protein (at different concentrations) were measured in FS-3 assay.

Observed MW

~96 kDa.

PROPERTIES

Form

Liquid

Buffer

PBS, 20% Glycerol

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (at least 1 month), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

batch dependent (Please refer to the vial label for the specific concentration.)

Region/Sequence

C-terminal 10 x His tagged ; 49-863 aa (Uniprot #Q13822)

Expression System

HEK293 cells

Purity

> 90% by SDS-PAGE

Endotoxin

< 1 EU/弮g (Determined by LAL assay)

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ectonucleotide pyrophosphatase/phosphodiesterase 2 , ATX , ATX-X , AUTOTAXIN , LysoPLD , NPP2 , PD-IALPHA , PDNP2

Cellular Localization

Secreted

Background

The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008]

Database

Research Area

DATA IMAGES

Human Autotaxin (mature) protein, His tag (active). GTX02798-pro

GTX02798-pro Image

SDS-PAGE of GTX02798-pro Human Autotaxin (mature) protein.

Human Autotaxin (mature) protein, His tag (active). GTX02798-pro

GTX02798-pro Functional Assay Image

The reaction rate of GTX02798-pro Human Autotaxin (mature) protein (at different concentrations) were measured in FS-3 assay.

REFERENCE

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REVIEW

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Package List Price ($)
$ 729