Human BAFF protein, human IgG1 Fc tag (active)

In vivo assay of restoration of the splenic T and B cell architecture in BAFF deficient mice using GTX05099-pro Human BAFF protein, human IgG1 Fc tag (active).
BAFF deficient mice were injected at day 0 with 100mg GTX05099-pro intravenously and at day 14 with 50mg GTX05099-pro intraperitoneal. At day 21, injected BAFF deficient mice were sacrificed together with WT and control BAFF deficient mice.
The splenic T and B cell architecture was analysed by IHC-Fr.
Figure A: Spleen sections of WT (left picture), BAFF deficient (middle picture) or injected BAFF deficient mice (right picture) were stained for IgM (red) and CD90 (green).
Figure B : Spleen sections of the same mice were stained for IgM (green) and MOMA (red).