APPLICATION
Application Note
Measured by its esterase activity. The specific activity is >500 pmoles/min/μg.
Observed MW
33 kDa.
PROPERTIES
Form
Lyophilized powder
Buffer
Batch dependent (please contact us for details)
Storage
Store at -20ºC or below. After reconstitution, keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
Region/Sequence
C-terminal polyhistidine tag; Ala 40-Ser 305 (NP_001730.1) fused with an Met at N-terminus
Expression System
E. coli
Purity
> 96 % by SDS-PAGE.
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
carbonic anhydrase 5A , CA5 , CA5AD , CAV , CAVA , GS1-21A4.1
Cellular Localization
Mitochondrion
Background
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VA is localized in the mitochondria and expressed primarily in the liver. It may play an important role in ureagenesis and gluconeogenesis. CA5A gene maps to chromosome 16q24.3 and an unprocessed pseudogene has been assigned to 16p12-p11.2. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX03503-pro Image
SDS-PAGE of GTX03503-pro Human CA5A (mature) protein, His tag (active).
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REFERENCE
There are currently no references for Human CA5A (mature) protein, His tag (active) (GTX03503-pro). Be the first to share your publications with this product.
REVIEW
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