Form
Liquid
Buffer
PBS pH 7.4, 10% glycerol
Preservative
No preservatives
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Region/Sequence
C-terminal His tagged, mature human CD66e protein (NP_004354, aa Lys35-Ala685)
Expression System
Baculovirus
Purity
>95% by SDS-PAGE
Endotoxin
< 1 EU/弮g (Determined by LAL assay)
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Synonyms
carcinoembryonic antigen related cell adhesion molecule 5 , CD66e , CEA
Cellular Localization
Cell membrane , Apical cell membrane , Cell surface
Background
This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Database
Research Area