25 mM Tris buffer (pH 7.2), 150 mM NaCl, 0.1 mM DTT, 50% glycerol.
Store as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
Full-length protein, N-terminal His-Tag; NP_008996.1
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
cell division cycle 37 , P50CDC37
The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008]