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Human CTLA4 protein, human IgG1 Fc tag (active)

Cat No. GTX65693-pro

Application

Functional Assay

Species

Human
Package
100 μg ($199)

APPLICATION

Application Note

Binds both CD80 (B7-1) and CD86 (B7-2) with high affinity and inhibits CD28 signaling competitively. Kills the target cell completely.

PROPERTIES

Form

Lyophilized powder

Buffer

Reconstitute with ddH₂O to 1mg/ml. Lyophilized from 0.2μm-filtered PBS.

Preservative

No preservative

Storage

Store at -20ºC or below. After reconstitution, keep as concentrated solution. Aliquot and avoid freeze-thaw cycles.

Region/Sequence

The extracellular domain of human CD152 [CTLA-4] (a.a. 37-160) is fused to the N-terminus of the Fc region of human IgG1.

Expression System

CHO cells

Purity

≥ 98% by SDS-PAGE.

Endotoxin

< 0.06 EU/μg

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

cytotoxic T-lymphocyte associated protein 4 , ALPS5 , CD , CD152 , CELIAC3 , CTLA-4 , GRD4 , GSE , IDDM12

Database

  • Gene ID: 1493 CTLA4

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 199