APPLICATION
Application Note
Binds both CD80 (B7-1) and CD86 (B7-2) with high affinity and inhibits CD28 signaling competitively. Kills the target cell completely.
PROPERTIES
Form
Lyophilized powder
Buffer
Reconstitute with ddH₂O to 1mg/ml. Lyophilized from 0.2μm-filtered PBS.
Preservative
No preservative
Storage
Store at -20ºC or below. After reconstitution, keep as concentrated solution. Aliquot and avoid freeze-thaw cycles.
Region/Sequence
The extracellular domain of human CD152 [CTLA-4] (a.a. 37-160) is fused to the N-terminus of the Fc region of human IgG1.
Expression System
CHO cells
Purity
≥ 98% by SDS-PAGE.
Endotoxin
< 0.06 EU/μg
Conjugation
Unconjugated
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
cytotoxic T-lymphocyte associated protein 4 , ALPS5 , CD , CD152 , CELIAC3 , CTLA-4 , GRD4 , GSE , IDDM12
Database
Research Area
REFERENCE
There are currently no references for Human CTLA4 protein, human IgG1 Fc tag (active) (GTX65693-pro). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Human CTLA4 protein, human IgG1 Fc tag (active) (GTX65693-pro). Be the first to share your experience with this product.