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Human Calcipressin 1 protein

Human Calcipressin 1 protein. GTX67361-pro

Cat No. GTX67361-pro

Species

Human
Package
100 μg ($359)

APPLICATION

Observed MW

28 kDa.

PROPERTIES

Form

Liquid

Buffer

20 mM Tris buffer (pH 7.5) with 0.1 M NaCl, 1 mM DTT.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Region/Sequence

Full length protein, MKLYFAQTLH IGSSHLAPPN PDKQFLISPP ASPPVGWKQV EDATPVINYD LLYAISKLGP GEKYELHAAT DTTPSVVVHV CESDQEKEEE EEMERMRRPK PKIIQTRRPE YTPIHLS

Expression System

E.coli

Purity

> 90% by SDS-PAGE.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

regulator of calcineurin 1 , ADAPT78 , CSP1 , DSC1 , DSCR1 , MCIP1 , RCN1

Background

The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]

Database

Research Area

DATA IMAGES

Human Calcipressin 1 protein. GTX67361-pro

GTX67361-pro Image

3μg Human Calcipressin 1 protein (GTX67361-pro) by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

REFERENCE

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REVIEW

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