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Human Cyclophilin B protein (active)

Human Cyclophilin B protein (active). GTX66955-pro

Cat. No. GTX66955-pro

Application

 Functional Assay

Species

 Human
Package
100 μg ($259)
See all Cyclophilin B protein products

APPLICATION

Application Note

Specific activity is > 1500 nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmole of suc-AAFP-PNA per minute at 37ºC in Tris-HCl (pH 8.0) using chymotrypsin.

PROPERTIES

Form

Liquid

Buffer

20mM Tris (pH8.0), 20mM NaCl, 0.5mM DTT, 10% Glycerol

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Region/Sequence

Length: 192 a.a. Sequence: MLLPGPSAAD EKKKGPKVTV KVYFDLRIGD EDVGRVIFGL FGKTVPKTVD NFVALATGEK GFGYKNSKFH RVIKDFMIQG GDFTRGDGTG GKSIYGERFP DENFKLKHYG PGWVSMANAG KDTNGSQFFI TTVKTAWLDG KHVVFGKVLE GMEVVRKVES TKTDSRDKPL KDVIIADCGK IEVEKPFAIA KE

Expression System

E. coli

Purity

> 95% by SDS-PAGE.

Endotoxin

< 1.0 EU/μg (determined by LAL method)

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

peptidylprolyl isomerase B , B , CYP-S1 , CYPB , HEL-S-39 , OI9 , SCYLP

Background

The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009]

Database

Research Area

DATA IMAGES

Human Cyclophilin B protein (active). GTX66955-pro

GTX66955-pro Image

3 μg of GTX66955-pro Human Cyclophilin B protein (active) by SDS-PAGE under reducing condition and visualized by coomassie blue stain

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Package List Price ($)
$ 259