GeneTex
  • Country / Location Selection

United States (US)

Human DR1 protein, His tag

Human DR1 protein, His tag. GTX67360-pro

Cat No. GTX67360-pro

Species

Human
Package
100 μg ($289)

APPLICATION

Observed MW

19 kDa.

PROPERTIES

Form

Liquid

Buffer

20 mM Tris-HCl buffer (pH 8.0) with 100 mM NaCl, 0.1 mM PMSF, 10% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Region/Sequence

Full length protein, N-terminal His-Tag; MGSSHHHHHH SSGLVPRGSH MASSSGNDDD LTIPRAAINK MIKETLPNVR VANDARELVV NCCTEFIHLI SSEANEICNK SEKKTISPEH VIQALESLGF GSYISEVKEV LQECKTVALK RRKASSRLEN LGIPEEELLR QQQELFAKAR QQQAELAQQE WLQMQQAAQQ AQLAAASASA SNQAGSSQDE EDDDDI

Expression System

E.coli

Purity

> 85% by SDS-PAGE.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

down-regulator of transcription 1 , NC2 , NC2-BETA , NC2B , NCB2

Cellular Localization

Nucleus

Background

This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Human DR1 protein, His tag. GTX67360-pro

GTX67360-pro Image

3μg Human DR1 protein (GTX67360-pro) by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

REFERENCE

There are currently no references for Human DR1 protein, His tag (GTX67360-pro). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Human DR1 protein, His tag (GTX67360-pro). Be the first to share your experience with this product.
SDS
Glycerol.pdf