APPLICATION
Application Note
Measured in a neutralizing assay using Jurkat human T lymphocyte. The ED₅₀ for this effect is less or equal to 10 ng/ml in the presence of 2 ng/ml TRAIL.
Observed MW
40-57 kDa.
PROPERTIES
Form
Liquid
Buffer
PBS, 10% Glycerol
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Region/Sequence
C-terminal hIgG-His-Tag; Length: 395 a.a. Sequence: ATIPRQDEVP QQTVAPQQQR RSLKEEECPA GSHRSEYTGA CNPCTEGVDY TIASNNLPSC LLCTVCKSGQ TNKSSCTTTR DTVCQCEKGS FQDKNSPEMC RTCRTGCPRG MVKVSNCTPR SDIKCKNESA ASSTGKTPAA EETVTTILGM LASPYHVEPK SCDKTHTCPP CPAPELLGGP
SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSRDEL TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ
QGNVFSCSVM HEALHNHYTQ KSLSLSPGKH HHHHH
Expression System
Baculovirus
Purity
> 90% by SDS-PAGE.
Endotoxin
< 1.0 EU/μg (determined by LAL method)
Conjugation
Unconjugated
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
TNF receptor superfamily member 10d , CD264 , DCR2 , TRAIL-R4 , TRAILR4 , TRUNDD
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX66967-pro Image
3 μg of GTX66967-pro Human DcR2 / CD264 protein (active) by SDS-PAGE under reducing condition and visualized by coomassie blue stain
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REFERENCE
There are currently no references for Human DcR2 / CD264 protein, human IgG1 Fc and His tag (active) (GTX66967-pro). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Human DcR2 / CD264 protein, human IgG1 Fc and His tag (active) (GTX66967-pro). Be the first to share your experience with this product.