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Human DcR2 / CD264 protein, human IgG1 Fc and His tag (active)

Human DcR2 / CD264 protein, human IgG1 Fc and His tag (active). GTX66967-pro

Cat No. GTX66967-pro

Application

Functional Assay

Species

Human
Package
10 μg ($219)

APPLICATION

Application Note

Measured in a neutralizing assay using Jurkat human T lymphocyte. The ED₅₀ for this effect is less or equal to 10 ng/ml in the presence of 2 ng/ml TRAIL.

Observed MW

40-57 kDa.

PROPERTIES

Form

Liquid

Buffer

PBS (pH 7.4) with 10% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml

Region/Sequence

C-terminal hIgG-His-Tag; Length: 395 a.a. Sequence: ATIPRQDEVP QQTVAPQQQR RSLKEEECPA GSHRSEYTGA CNPCTEGVDY TIASNNLPSC LLCTVCKSGQ TNKSSCTTTR DTVCQCEKGS FQDKNSPEMC RTCRTGCPRG MVKVSNCTPR SDIKCKNESA ASSTGKTPAA EETVTTILGM LASPYHVEPK SCDKTHTCPP CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSRDEL TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGKH HHHHH

Expression System

Baculovirus

Purity

> 90% by SDS-PAGE.

Endotoxin

< 1.0 EU/μg (determined by LAL method)

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

TNF receptor superfamily member 10d , CD264 , DCR2 , TRAIL-R4 , TRAILR4 , TRUNDD

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis. [provided by RefSeq, Jul 2008]

Database

  • Gene ID: 8793 TNFRSF10D
  • UniProt: Q9UBN6 TNFRSF10D

Research Area

DATA IMAGES

Human DcR2 / CD264 protein, human IgG1 Fc and His tag (active). GTX66967-pro

GTX66967-pro Image

3 μg of GTX66967-pro Human DcR2 / CD264 protein (active) by SDS-PAGE under reducing condition and visualized by coomassie blue stain

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Package List Price ($)
$ 219