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Human Defensin Alpha 1 protein (active)

Cat No. GTX48210-pro

Application

Functional Assay

Species

Human
Package
20 μg ($369)
PRODUCT

Summary

Recombinant human NP-1 is a 3.4 kDa protein containing 30 amino acid residues.

APPLICATION

Application Note

Determined by its ability to chemoattract immature dendritic cells using a concentration of 1.0-10.0 ng/ml.

PROPERTIES

Form

Lyophilized powder

Buffer

Batch dependent (please contact us for details)

Storage

Store at -20ºC or below. After reconstitution, keep as concentrated solution. Avoid freeze-thaw cycles.

Region/Sequence

ACYCRIPACI AGERRYGYCI YQGRLWAFCC

Expression System

E. Coli

Purity

> 98%

Endotoxin

< 1 EU/μg

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

defensin alpha 1 , DEF1 , DEFA2 , HNP-1 , HP-1 , HP1 , MRS

Background

Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subjec be icopy number variation. [provided by RefSeq, Oc b2014]

Database

  • Gene ID: 1667 DEFA1

Research Area

REFERENCE

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REVIEW

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Package List Price ($)
$ 369