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Human FAP protein, His tag (active)

Human FAP protein, His tag (active). GTX02866-pro

Cat No. GTX02866-pro

Application

Functional Assay

Species

Human
Package
50 μg ($469)

APPLICATION

Application Note

Specific activity is > 5,000 pmol/min/μg, and is defined as the amount of enzyme that hydrolysis 1.0 pmole of Z-GP-AMC per minute at pH 7.5, at 37ºC.

Calculated MW

88 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS (pH 7.4), 20% glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1 week), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.25 mg/ml (Please refer to the vial label for the specific concentration.)

Region/Sequence

His-Tagged; 26-760aa (Q12884, NP_004451.2)

Expression System

Baculovirus

Purity

> 90% by SDS-PAGE

Endotoxin

< 1.0 EU/μg (determined by LAL method)

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

fibroblast activation protein alpha , DPPIV , FAPA , FAPalpha , SIMP

Background

The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]

Database

Research Area

DATA IMAGES

Human FAP protein, His tag (active). GTX02866-pro

GTX02866-pro Image

SDS-PAGE analysis of 3μg GTX02866-pro Human FAP protein, His tag (active) under reducing condition.

REFERENCE

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REVIEW

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