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Human FGFR4 (extracellular region) protein, His tag

Human FGFR4 (extracellular region) protein, His tag. GTX02787-pro

Cat. No. GTX02787-pro

Species

 Human
Package
50 μg ($429)
See all FGFR4 protein products

APPLICATION

Observed MW

~55 kDa.

PROPERTIES

Form

Liquid

Buffer

PBS, 20% Glycerol

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (at least 1 month), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

batch dependent (Please refer to the vial label for the specific concentration.)

Region/Sequence

C-terminal 10 x His tagged ; 22-369 aa (Uniprot #P22455)

Expression System

HEK293 cells

Purity

> 95% by SDS-PAGE

Endotoxin

< 1 EU/弮g (Determined by LAL assay)

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

fibroblast growth factor receptor 4 , CD334 , JTK2 , TKF

Cellular Localization

Cell membrane; Single-pass type I membrane protein , Endosome , Endoplasmic reticulum

Background

The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Human FGFR4 (extracellular region) protein, His tag. GTX02787-pro

GTX02787-pro Image

SDS-PAGE of GTX02787-pro Human FGFR4 (extracellular region) protein.

REFERENCE

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Package List Price ($)
$ 429