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Human Flt3 Ligand protein, His tag (active)

Human Flt3 Ligand protein, His tag (active). GTX01213-pro
Human Flt3 Ligand protein, His tag (active). GTX01213-pro

Cat No. GTX01213-pro

Application

Functional Assay

Species

Human
Package
20 μg ($329),
10 μg ($249)

APPLICATION

Application Note

Measured in a cell proliferation assay using BaF3 cells transfected with mouse Flt-3 protein. The ED₅₀ for this effect is typically 2-11 ng/ml.

Observed MW

27 kDa.

PROPERTIES

Form

Lyophilized powder

Buffer

Batch dependent (please contact us for details)

Storage

Store at -20ºC or below. After reconstitution, keep as concentrated solution. Avoid freeze-thaw cycles.

Region/Sequence

N-terminal poly His tagged; Thr27-Pro185 of Human Flt3 Ligand protein (P49771-1)

Expression System

Baculovirus (Insect cells)

Purity

> 95% by SDS-PAGE.

Endotoxin

< 1.0 EU/μg (determined by LAL method)

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

FL,FLG3L,FLT3L

Background

Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011]

Database

Research Area

DATA IMAGES

Human Flt3 Ligand protein, His tag (active). GTX01213-pro

GTX01213-pro Functional Assay Image

The protein activity of GTX01213-pro Human Flt3 Ligand protein was measured in a cell proliferation assay using BaF3 cells transfected with mouse Flt­3.
ED₅₀ : 2-11 ng/ml

Human Flt3 Ligand protein, His tag (active). GTX01213-pro

GTX01213-pro Image

SDS-PAGE of 5 μg GTX01213-pro Human Flt3 Ligand protein, His tag (active).

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