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Human GM-CSF Receptor alpha protein, His tag (active)

Human GM-CSF Receptor alpha protein, His tag (active). GTX67018-pro

Cat No. GTX67018-pro

Application

Functional Assay

Species

Human
Package
5 μg ($249)

APPLICATION

Application Note

Measured by its ability to inhibit GM-CSF dependent proliferation of TF1 human erythroleukemic cells. The ED₅₀ for this effect is less or equal to 10 μg/ml in the presence of 0.5 ng/ml GM-CSF.

Observed MW

40-57 kDa.

PROPERTIES

Form

Liquid

Buffer

PBS (pH7.4), 10% Glycerol

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml

Region/Sequence

C-terminal His-Tag; Length: 310 a.a. Sequence: ADPLIPEKSD LRTVAPASSL NVRFDSRTMN LSWDCQENTT FSKCFLTDKK NRVVEPRLSN NECSCTFREI CLHEGVTFEV HVNTSQRGFQ QKLLYPNSGR EGTAAQNFSC FIYNADLMNC TWARGPTAPR DVQYFLYIRN SKRRREIRCP YYIQDSGTHV GCHLDNLSGL TSRNYFLVNG TSREIGIQFF DSLLDTKKIE RFNPPSNVTV RCNTTHCLVR WKQPRTYQKL SYLDFQYQLD VHRKNTQPGT ENLLINVSGD LENRYNFPSS EPRAKHSVKI RAADVRILNW SSWSEAIEFG SDDGHHHHHH

Expression System

Baculovirus

Purity

> 90% by SDS-PAGE.

Endotoxin

< 1.0 EU/μg (determined by LAL method)

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

colony stimulating factor 2 receptor alpha subunit , CD116 , CDw116 , CSF2R , CSF2RAX , CSF2RAY , CSF2RX , CSF2RY , GM-CSF-R-alpha , GMCSFR , GMR , SMDP4 , alphaGMR

Background

The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Human GM-CSF Receptor alpha protein, His tag (active). GTX67018-pro

GTX67018-pro Image

3 μg of GTX67018-pro Human GM-CSF Receptor alpha protein (active) by SDS-PAGE under reducing condition and visualized by coomassie blue stain

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Package List Price ($)
$ 249