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Human HSC70 protein (active)

Human HSC70 protein (active). GTX00438-pro

Cat No. GTX00438-pro

Application Functional Assay
Species Human
Package
50 μg ($249)
APPLICATION

Application Note

The protein has ATPase activity at the time of manufacture of 3.2 μM phosphate liberated/hr/μg protein in a 200 μl reaction at 37ºC (pH 8.0) in the presence of 20 μl of 1 mM ATP using a Malachite Green assay.

Observed MW

73 kDa.
PROPERTIES

Form

Liquid

Buffer

50 mM Tris/HCl (pH 8.0), 300 mM NaCl.

Storage

Store as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.

Concentration

Batch dependent

Region/Sequence

His-Tag protein

Expression System

E. coli

Purification

Affinity Purified

Purity

> 90%

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

heat shock protein family A (Hsp70) member 8,HEL-33,HEL-S-72p,HSC54,HSC70,HSC71,HSP71,HSP73,HSPA10,LAP-1,LAP1,NIP71

Background

This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

Database

Research Area

DATA IMAGES
Human HSC70 protein (active). GTX00438-pro

GTX00438-pro Image

SDS-PAGE analysis of GTX00438-pro Human HSC70 protein (active).

REFERENCE
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REVIEW
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Package List Price ($)
$ 249