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Human HSP27 protein

Human HSP27 protein. GTX00439-pro

Cat No. GTX00439-pro

Species Human
Package
50 μg ($219)
APPLICATION

Observed MW

27 kDa.
PROPERTIES

Form

Liquid

Buffer

20 mM Tris/HCl (pH 7.5), 450 mM NaCl, 10% glycerol, 5 mM DTT.

Storage

Store as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.

Concentration

Batch dependent

Region/Sequence

Full-length protein without any tag; NP_001531.1

Expression System

E. coli

Purification

Affinity Purified

Purity

> 90%

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

heat shock protein family B (small) member 1,CMT2F,HEL-S-102,HMN2B,HS.76067,HSP27,HSP28,Hsp25,SRP27

Background

This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES
Human HSP27 protein. GTX00439-pro

GTX00439-pro Image

SDS-PAGE analysis of GTX00439-pro Human HSP27 protein.

REFERENCE
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Package List Price ($)
$ 219