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Human HSP60 protein (active)

Human HSP60 protein (active). GTX00440-pro

Cat No. GTX00440-pro

Application Functional Assay
Species Human
Package
50 μg ($249)
APPLICATION

Application Note

The protein has ATPase activity at the time of manufacture of 3.6 μM phosphate liberated/hr/μg protein in a 200 μl reaction at 37ºC (pH 7.5) in the presence of 20 μl of 1 mM ATP using a Malachite Green assay.

Observed MW

60 kDa.
PROPERTIES

Form

Liquid

Buffer

20 mM Phosphate Buffer, 150 mM NaCl, 10% glycerol.

Storage

Store as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.

Concentration

Batch dependent

Region/Sequence

His-Tag protein

Expression System

E. coli

Purification

Affinity Purified

Purity

> 90%

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

heat shock protein family D (Hsp60) member 1,CPN60,GROEL,HLD4,HSP-60,HSP60,HSP65,HuCHA60,SPG13

Background

This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq, Jun 2010]

Database

Research Area

DATA IMAGES
Human HSP60 protein (active). GTX00440-pro

GTX00440-pro Image

SDS-PAGE analysis of GTX00440-pro Human HSP60 protein (active).

REFERENCE
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REVIEW
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Package List Price ($)
$ 249