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Human IL1 beta protein, His tag

Human IL1 beta protein, His tag. GTX138452-pro

Cat. No. GTX138452-pro

Species

 Human
Package
100 μg ($499)
See all IL1 beta protein products

APPLICATION

Observed MW

27 kDa.

PROPERTIES

Form

Lyophilized powder

Buffer

Reconstitute with distilled water to 0.9 mg/ml. Lyophilized from PBS, 2% Trehalose, 5% Mannitol, 0.01% Tween-80.

Preservative

No Preservative

Storage

Store at 4ºC or below. After reconstitution, keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. For long-term storage after reconstitution, aliquot and store at -70ºC or below. Do not vortex.

Region/Sequence

C-terminal His tagged full-length Human IL1B protein (1-269aa of NP_000567.1)

Expression System

HEK293 cells

Purity

>95%

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

interleukin 1 beta , IL-1 , IL1-BETA , IL1F2

Cellular Localization

Cytoplasm, cytosol,Lysosome,Secreted

Background

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Human IL1 beta protein, His tag. GTX138452-pro

GTX138452-pro Image

GTX138452-pro Human IL1 beta, His tag was analyzed using SDS-PAGE and stained with coomassie blue and captured by monochrome camera.

REFERENCE

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REVIEW

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Package List Price ($)
$ 499