APPLICATION
Application Note
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED₅₀ for this effects is less or equal to 1.5 ng/ml.
Observed MW
13.5-18 kDa.
PROPERTIES
Form
Liquid
Buffer
PBS, 10% Glycerol
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Region/Sequence
C-terminal His-Tag; Length: 124 a.a. Sequence: ADPIPTEIPT SALVKETLAL LSTHRTLLIA NETLRIPVPV HKNHQLCTEE IFQGIGTLES QTVQGGTVER LFKNLSLIKK YIDGQKKKCG
EERRRVNQFL DYLQEFLGVM NTEWIIESHH HHHH
Expression System
Baculovirus
Purity
> 90% by SDS-PAGE.
Endotoxin
< 1.0 EU/μg (determined by LAL method)
Conjugation
Unconjugated
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
interleukin 5 , EDF , IL-5 , TRF
Background
This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq, Jul 2013]
Database
Research Area
DATA IMAGES
|
GTX67068-pro Image
3 μg of GTX67068-pro Human IL5 protein (active) by SDS-PAGE under reducing condition and visualized by coomassie blue stain
|
REFERENCE
There are currently no references for Human IL5 protein, His tag (active) (GTX67068-pro). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Human IL5 protein, His tag (active) (GTX67068-pro). Be the first to share your experience with this product.