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Human IL5 protein, His tag

Human IL5 protein, His tag. GTX139317-pro

Cat. No. GTX139317-pro

Species

 Human
Package
100 μg ($499)
See all Human IL5 protein products

APPLICATION

Observed MW

20 kDa.

PROPERTIES

Form

Lyophilized powder

Buffer

Reconstitute with distilled water to 1.5 mg/ml. Lyophilized from PBS, 2% Trehalose, 5% Mannitol, 0.01% Tween-80.

Preservative

No Preservative

Storage

Store at 4ºC or below. After reconstitution, keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. For long-term storage after reconstitution, aliquot and store at -70ºC or below. Do not vortex.

Region/Sequence

C-terminal His tagged Human IL5 protein (1-134 a.a. of NP_000870.1)

Expression System

HEK293 cells

Purity

>85%

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

interleukin 5 , EDF , IL-5 , TRF

Cellular Localization

Secreted

Background

This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq, Jul 2013]

Database

Research Area

DATA IMAGES

Human IL5 protein, His tag. GTX139317-pro

GTX139317-pro Image

GTX139317-pro Human IL5 protein, His tag was analyzed using SDS-PAGE and stained with coomassie blue and captured by monochrome camera.
The predicted molecular weight determined by ESI-TOF is 13206.27 Da (+/- 10 Da by ESI-TOF). The observed MW is 13208.40 Da. Additional masses at 13411.42 Da and 13776.69 Da are observed due to residual O-glycans.

REFERENCE

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REVIEW

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Package List Price ($)
$ 499