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Human JNK3 protein, His tag

Human JNK3 protein, His tag. GTX67680-pro

Cat No. GTX67680-pro

Species

Human
Package
10 μg ($289)

APPLICATION

Observed MW

53 kDa.

PROPERTIES

Form

Liquid

Buffer

PBS (pH 7.4) with 30% glycerol, 1 mM DTT, 0.1 mM PMSF.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.25 mg/ml (Please refer to the vial label for the specific concentration.)

Region/Sequence

Full length protein, C-terminal His-Tag; MSLHFLYYCS EPTLDVKIAF CQGFDKQVDV SYIAKHYNMS KSKVDNQFYS VEVGDSTFTV LKRYQNLKPI GSGAQGIVCA AYDAVLDRNV AIKKLSRPFQ NQTHAKRAYR ELVLMKCVNH KNIISLLNVF TPQKTLEEFQ DVYLVMELMD ANLCQVIQME LDHERMSYLL YQMLCGIKHL HSAGIIHRDL KPSNIVVKSD CTLKILDFGL ARTAGTSFMM TPYVVTRYYR APEVILGMGY KENVDIWSVG CIMGEMVRHK ILFPGRDYID QWNKVIEQLG TPCPEFMKKL QPTVRNYVEN RPKYAGLTFP KLFPDSLFPA DSEHNKLKAS QARDLLSKML VIDPAKRISV DDALQHPYIN VWYDPAEVEA PPPQIYDKQL DEREHTIEEW KELIYKEVMN SEEKTKNGVV KGQPSPSGAA VNSSESLPPS SSVNDISSMS TDQTLASDTD SSLEASAGPL GCCRHHHHHH

Expression System

Baculovirus

Purity

> 85% by SDS-PAGE.

Endotoxin

< 0.1 EU/μg (determined by LAL method)

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

mitogen-activated protein kinase 10 , JNK3 , JNK3A , PRKM10 , SAPK1b , p493F12 , p54bSAPK

Cellular Localization

Cytoplasm,Membrane,Nucleus,Mitochondrion

Background

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals, and thus are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system, and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]

Database

Research Area

DATA IMAGES

Human JNK3 protein, His tag. GTX67680-pro

GTX67680-pro Image

3μg Human JNK3 protein (GTX67680-pro) by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf