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Human LIF protein, His tag (active)

Human LIF protein, His tag (active). GTX67087-pro

Cat. No. GTX67087-pro

Application

 Functional Assay

Species

 Human
Package
10 μg ($219)
See all LIF protein products

APPLICATION

Application Note

Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED₅₀ for this effects is less or equal to 0.5 ng/ml.

Observed MW

18-40 kDa.

PROPERTIES

Form

Liquid

Buffer

PBS, 10% Glycerol

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.25 mg/ml (Please refer to the vial label for the specific concentration.)

Region/Sequence

C-terminal His-Tag; Length: 189 a.a. Sequence: ADPSPLPITP VNATCAIRHP CHNNLMNQIR SQLAQLNGSA NALFILYYTA QGEPFPNNLD KLCGPNVTDF PPFHANGTEK AKLVELYRIV VYLGTSLGNI TRDQKILNPS ALSLHSKLNA TADILRGLLS NVLCRLCSKY HVGHVDVTYG PDTSGKDVFQ KKKLGCQLLG KYKQIIAVLA QAFHHHHHH

Expression System

Baculovirus

Purity

> 90% by SDS-PAGE.

Endotoxin

< 1.0 EU/μg (determined by LAL method)

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

LIF interleukin 6 family cytokine , CDF , DIA , HILDA , MLPLI

Background

The protein encoded by this gene is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]

Database

Research Area

DATA IMAGES

Human LIF protein, His tag (active). GTX67087-pro

GTX67087-pro Image

3 μg of GTX67087-pro Human LIF protein (active) by SDS-PAGE under reducing condition and visualized by coomassie blue stain

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SDS
PBS.pdf
Glycerol.pdf
Package List Price ($)
$ 219