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Human MMP26 protein (active)

Human MMP26 protein (active). GTX03552-pro

Cat. No. GTX03552-pro

Application

Functional Assay

Species

Human
Package
100 μg ($399)

APPLICATION

Application Note

Measured by its ability to cleave the fluorogenic peptide substrate, Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2. The specific activity is > 60 pmol/min/μg.

Observed MW

19 kDa.

PROPERTIES

Form

Lyophilized powder

Buffer

Batch dependent (please contact us for details)

Storage

Store at -20ºC or below. After reconstitution, keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.

Region/Sequence

No tag; Thr90-Pro261 (NP_068573.2)

Expression System

E. coli

Purity

> 90 % by SDS-PAGE.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

matrix metallopeptidase 26

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme may degrade collagen type IV, fibronectin, fibrinogen, and beta-casein, and activate matrix metalloproteinase-9 by cleavage. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The encoded protein may promote cell invasion in multiple human cancers. [provided by RefSeq, May 2016]

Database

Research Area

DATA IMAGES

Human MMP26 protein (active). GTX03552-pro

GTX03552-pro Image

SDS-PAGE of GTX03552-pro human MMP26 protein (active).

REFERENCE

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REVIEW

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Package List Price ($)
$ 399