APPLICATION
Application Note
The ED₅₀ for this effect is 0.5 - 1.5 ng/ml. Measured in a cell proliferation assay using MCF7 cells.
PROPERTIES
Form
Liquid
Buffer
20mM Tris-HCl buffer (pH8.0), 0.1mM PMSF, 10% Glycerol
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Region/Sequence
Full length protein, C-terminal His-Tag; Length: 402 a.a. Sequence: MSREMQDVDL AEVKPLVEKG ETITGLLQEF DVQEQDIETL HGSVHVTLCG TPKGNRPVIL TYHDIGMNHK TCYNPLFNYE DMQEITQHFA VCHVDAPGQQ DGAASFPAGY MYPSMDQLAE MLPGVLQQFG LKSIIGMGTG AGAYILTRFA LNNPEMVEGL VLINVNPCAE GWMDWAASKI SGWTQALPDM VVSHLFGKEE MQSNVEVVHT YRQHIVNDMN PGNLHLFINA YNSRRDLEIE RPMPGTHTVT LQCPALLVVG DSSPAVDAVV ECNSKLDPTK TTLLKMADCG GLPQISQPAK LAEAFKYFVQ GMGYMPSASM TRLMRSRTAS GSSVTSLDGT RSRSHTSEGT RSRSHTSEGT RSRSHTSEGA HLDITPNSGA AGNSAGPKSM EVSCLEHHHH HH
Expression System
E. coli
Purity
> 95% by SDS-PAGE.
Conjugation
Unconjugated
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
N-myc downstream regulated 1 , CAP43 , CMT4D , DRG-1 , DRG1 , GC4 , HMSNL , NDR1 , NMSL , PROXY1 , RIT42 , RTP , TARG1 , TDD5
Background
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
Database
Research Area
DATA IMAGES
|
GTX67094-pro Image
3 μg of GTX67094-pro Human NDRG1 protein (active) by SDS-PAGE under reducing condition and visualized by coomassie blue stain
|
REFERENCE
There are currently no references for Human NDRG1 protein, His tag (active) (GTX67094-pro). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Human NDRG1 protein, His tag (active) (GTX67094-pro). Be the first to share your experience with this product.